Scientific publications

Since its inception, CIPHE has contributed to more than 150 publications in peer-reviewed journals. The team has also participated in nearly fifty international conferences, presenting their work through oral communications and posters. The seven publications highlighted below illustrate a fraction of CIPHE’s extensive scientific output, and are directly derived from the technological research developed at the center.

bioRxiv

Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors

Demerle C, Gorvel L, Mello M, et al.

2022

Preclinical mice and rat model generation

Functional immunomics for mechanistic insights of therapeutic targets

Modeling infectious diseases for innovative therapies

Mouse colony management

Administration and infrastructure core

Scientific publications

bioRxiv

Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors

Demerle C, Gorvel L, Mello M, et al.

EMBO Journal

Single-cell transcriptomics uncovers an instructive T-cell receptor role in adult γδ T-cell lineage commitment

Scaramuzzino S, Potier D, Ordioni R, et al.

EBioMedicine

Design, immunogenicity, and efficacy of a pan-sarbecovirus dendritic-cell targeting vaccine

Coléon S, Wiedemann A, Surénaud M, et al.

J Exp Med

Systems-level conservation of the proximal TCR signaling network of mice and humans

Nicolas P, Ollier J, Mori D, et al.

Immunity

Meningeal macrophages protect against viral neuroinfection

Rebejac J, Eme-Scolan E, Paroutaud L, et al.

Front Immunol

Conditional Deletion of Pdcd1 Identifies the Cell-Intrinsic Action of PD-1 on Functional CD8 T Cell Subsets for Antitumor Efficacy

Raghavan S, Tovbis-Shifrin N, Kochel C, et al.

Lancet

Loss of KDM1A in GIP-dependent primary bilateral macronodular adrenal hyperplasia with Cushing’s syndrome: a multicentre, retrospective, cohort study

Chasseloup F, Bourdeau I, Tabarin A, et al.

Nature Immunology

Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections

Ngo C, Pierini-Malosse C, Rahmani K, Zarubica A, et al.

Cancer Immunology Immunotherapy

High baseline PD-1+ CD8 T Cells and TIGIT+ CD8 T Cells in circulation associated with response to PD-1 blockade in patients with non-small cell lung cancer

Dutta N, Svensson J, Saad GA, Luche H, et al.

Oncoimmunology

Characterization of the immune landscape in healthy mouse prostate and during prostate cancer progression

Pervizou D, De Chiara J, Spinelli L, Fiore F, et al.

J Exp Med

A CARMIL2 gain-of-function mutation suffices to trigger most CD28 costimulatory functions in vivo

Zhang F, Celis-Gutierrez J, Zhang L, Fiore F, et al.

Nature Communications

Improving laboratory animal genetic reporting: LAG-R guidelines

Teboul L, Amos-Landgraf J, Benavides FJ, et al.

Science

The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants

Materna M, Delmonte OM, Bosticardo M, Luche H et al.

J Neuroinflammation

Cytomegalovirus infection of the fetal brain: intake of aspirin during pregnancy blunts neurodevelopmental pathogenesis in the offsprin

Tarhini S, Crespo-Quiles C, Buhler E, Luche H, et al.

JHEP Rep

Placental growth factor modulates endothelial NO production and exacerbates experimental hepatopulmonary syndrome

Robert F, Benchenouf F, Ha MN, Fiore F, et al.

Frontiers in Cellular and Infection Microbiology

A novel mass cytometry protocol optimized for immunophenotyping of low-frequency antigen-specific T cells

Balz K, Grange M, Pegel U, Luche H, et al.

J Immunotherapy Cancer

Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors

Demerlé C, Gorvel L, Mello M, Zarubica A, et al.

Mamm Genome

INFRAFRONTIER quality principles in systemic phenotyping

Ehlich H, Cater HL, Flenniken AM, Zarubica A, et al.

European Journal of Immunology

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Cossarizza A, Chang HD, Radbruch A, et al.

EMBO Journal

Single-cell transcriptomics uncovers an instructive T-cell receptor role in adult γδ T-cell lineage commitment

Scaramuzzino S, Potier D, Ordioni R,Luche H, et al.