P4
Mouse colony management

Comprehensive colony management services
The CIPHE Central Mouse Clinic ensures the highest standards of animal care and experimentation, offering comprehensive colony management, breeding, rederivation, cryorecovery, and cryoarchiving services. Committed to ethical research, CIPHE integrates rigorous welfare assessments and continuous monitoring while adhering to European regulations and the 3Rs principle.
365
days a year
+ 2,000
unique lines
+ 50,000
mice
Breeding, housing & animal experimentation
This platform is designed with client-focused solutions at its core. It enables research teams to benefit from expert guidance tailored to their specific needs, including customized breeding strategies, complex crossings to generate novel models, and batch production planning aligned with experimental timelines. In addition, the platform offers consulting in experimental design to optimize study outcomes while ensuring strict adherence to ethical standards.
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Safeguard mouse lines through sperm cryopreservation, rederivation from embryos or sperm, and efficient recovery. A cost-effective, long-term strategy to mitigate genetic drift, breeding disruptions, and strain loss.
Cryopreservation, Rederivation & Recovery
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With + 50,000 mice, and over 2,000 unique lines, CIPHE offers dedicated labs, sterile zones, semi-robotic cage cleaning, and a digital interface for project tracking. The "1 cage = 1 client" model ensures traceability and quality.
Advanced infrastructure & streamlined logistics
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CIPHE coordinates national and international shipments of live mice, embryos, and sperm. Services include logistics, customs documents, veterinary health certificates, and compliance with all relevant regulations.
International transport & regulatory support
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Strict adherence to EU Directive 2010/63, ISO 9001 certified quality management, 3Rs implementation (Replacement, Reduction, Refinement), internal ethics committee, and robust welfare monitoring systems.
Ethics & animal welfare commitment
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From importation and colony reactivation to custom cohort production and final archiving, CIPHE supports each project phase. Efficient batch management minimizes costs, prevents overproduction, and optimizes space.
End-to-end project support
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For academic or industrial research, CIPHE ensures reliable, ethical, and high-standard colony management. Focus on your science while we manage the preservation, breeding, and global distribution of your murine models.
Why partner with CIPHE?
Built-in expertise
Trusted by global research institutions and leading biotech companies.






